Doane, who was taken by the Cleveland Indians in this year's amateur draft and plays for the Mahoning Valley Scrappers, came on in the fourth inning of a 4-1, rain-shortened win over the Auburn Doubledays. The right-hander threw three innings, allowing no runs and giving up just one hit. He coaxed seven groundouts and two flyouts in his stint.
Doane (1-0) followed the one inning thrown by Cleveland closer Chris Perez, who made a rehab appearance in Tuesday's ballgame.
Rain halted the game after eight innings. Auburn starter Deion Williams (0-2) took the loss.
The Scrappers and Doubledays compete in the New York-Penn League, the oldest continuously operated Class A league in professional baseball.