It was torn down as part of the plea deal that spared Ariel Castro a possible death sentence and forced him to turn over the deed to the house and pay for it to be razed. He was sentenced last week to life in prison plus 1,000 years.
But the question remains: How could the crimes go unnoticed so long in Castro's blue-collar neighborhood?
One of the women imprisoned there, Michelle Knight, showed up early Wednesday before the work began. She made a brief statement and released balloons into the air.
"Dear Lord, give the missing people strength and power to know that they are loved," said Knight, who had rosary beads hanging from her neck.
"We hear their cry, they are never forgotten in my heart. They are caterpillars, waiting to turn into a butterfly. They are never forgotten, they are loved."
Knight said the array of balloons "represents all the millions of children that were never found and the ones that passed away that were never heard."
There was applause as a relative of one victim represented the three and took the controls of the wrecking crane for the first smash into the top of the front wall. Later, as the house debris disappeared into the basement, church bells rang.
Katie Mae Brown, 62, a former resident of the street, said tearing the house down was important for the neighborhood to show "that monster — that he is behind bars and that he's never going to get out."
Cuyahoga County prosecutor Tim McGinty said the two houses to the left of Castro's would also be torn down and developed into a park or whatever the residents decide.
Prosecutors say Castro cried when he signed over the house deed and mentioned his "many happy memories" there with the women. They highlighted the teary-eyed scene to illustrate Castro's "distorted and twisted" personality.
On Wednesday, McGinty called him "one evil guy."
Family members, including his son, Anthony Castro, went to the house Monday and picked up personal items including old photographs, guitars and bicycles.
Relatives said the house razing was part of the healing process for them. "It's sad and hard but it is necessary for us to move on," Anthony Castro told WKYC-TV.
The three women disappeared separately between 2002 and 2004, when they were 14, 16 and 20 years old. Each had accepted a ride from Castro.
They escaped May 6, when Amanda Berry, now 27, broke part of a door and yelled to neighbors for help. Castro was arrested that evening.
At Castro's sentencing, prosecutors displayed photos that provided a first glimpse inside the rooms where the women lived.
Stuffed animals lined the bed and crayon drawings were taped to the wall where Berry lived with her young daughter, who was fathered by Castro. One of the drawings on a shelf said, "Happy Birthday."
The window was boarded shut and door knobs had been removed and replaced with multiple locks. Saucer-size holes in inside doors were meant for circulation.
Another room, shared by Knight and Gina DeJesus, had a portable toilet, a clock radio and several chains.
The house, which quickly became a drive-by attraction after the women fled to freedom, was fenced off and kept under 24-hour police guard amid arson threats.