The defendants are scheduled for report dates before U.S. District Judge John Fowlkes on Friday morning.
Prosecutors say people were paid to take Praxis certification exams on behalf of current or aspiring teachers in Arkansas, Mississippi and Tennessee over a 15-year period. The teachers then allegedly used their passing grades on the exams to get jobs in public schools.
Those charged with fraud in the case are either accused of taking the tests in return for payment, or are teachers accused of hiring alleged ringleader Clarence Mumford Sr. to arrange for someone to take the exams for them.
Mumford has a change-of-plea hearing later this month.