The crash occurred about 2:11 p.m. near the Wilcox Drive exit, according to Kingsport Police Department Patrolman Dale Farmer.
The driver has been identified as James W. Brooks, 38, of Rogersville.
Brooks was westbound at a high rate of speed in a red Ford pickup when he ran off the edge of the road and then overcorrected, Farmer said. The truck then spun around and rolled onto its side in westbound traffic.
The driver was transported with injuries that were not deemed life-threatening, Farmer said.
There were “possible indications” that drugs and alcohol may have been factors in the crash, according to Farmer.
The accident reduced I-26 to one lane on each side while emergency crews cleared the scene.
While emergency crews were cleaning up that wreck scene, a second crash occurred near the Rock Springs Drive exit, Farmer said.
The latter incident occurred about 2:53 p.m.
A green Toyota pickup driven by Joshua Ramsey, 28, Kingsport, was stopped in the righthand westbound lane due to traffic slowed for the crash at the Wilcox Drive exit.
Behind him there was a 2006 Pontiac Vibe driven by Kimberly Mason, 36, Gray, and a 2008 Kia Spectra occupied by driver Claude Frye, 53, and his wife, Ada Frye, 54, both of Piney Flats.
Samantha M. Cravens, 19, Johnson City, told police she had looked down at the radio in her 1998 Saturn as she approached the wreck scene. When she looked up, she discovered traffic had stopped.
The Saturn struck the Fryes’ car at an estimated speed of between 60 to 70 mph, causing extensive damage to both cars. The other vehicles had minor damage.
The Fryes and Cravens were taken to a local hospital for treatment. As of about 6 p.m., hospital staff said the Fryes had been discharged and Cravens’ condition had not yet been determined.
Mason also reported injury but refused treatment.